您现在在位置: » 内容
培美曲塞治疗肺腺癌的应用分析
作者: 刘品一1,马显军2,朱 巍1 来源:《转化医学电子杂志》 2017-12-01

  【Abstract】 As an anti⁃tumor drug, pemetrexed can block the metabolic pathway of folate through multiple targets, thus effectively controlling tumor growth. It can be used in first⁃line chemotherapy, patients with advanced chemotherapy and neoadjuvant chemotherapy, with small adverse reactions and good curative effect. In this paper, the factors affecting the prognosis and the clinical value of pemetrexed are reviewed from different perspectives.

  【Keywords】 lung adenocarcinoma; pemetrexed; mechanism of action; adverse reactions; treatment

  【摘 要】 培美曲塞作为一种抗肿瘤药能够多靶点阻断叶酸代谢途径,从而有效地控制肿瘤生长. 培美曲塞可以用于一线化疗、既往化疗进展后的患者及新辅助化疗,不良反应小,疗效好. 本文从多角度全面综述了培美曲塞的临床应用价值及影响预后的因素.

  【关键词】 肺腺癌;培美曲塞;作用机制;不良反应;治疗

  【中图分类号】 R734.2 【文献标识码】 A

  阅读原文:www.ejotm.com/ch/reader/view_abstract.aspx